Revolutionizing Life Science: An Interview with SCIEX

SCIEX just lately attended ASMS 2024. What have been the highlights of the convention and what have been you excited to announce while there?

Chris Lock: You may really feel an vitality this 12 months paying homage to pre-pandemic occasions. Attendees sought connection and actually wished to know how new improvements will assist them be quicker and produce higher insights and in addition focus on with us how they count on their future must evolve.

In case you have been to ASMS, you already know that nighttime hospitality suites are stuffed with enjoyable, participating actions. SCIEX showcased our Quant Continuum collection—three quick movies masking our launches performed all through the evening and engaged the gang via reactive wristbands.

Jose Castro-Perez: We additionally had 3 thrilling bulletins this 12 months at ASMS. You may learn the bulletins in full right here:

• The launch of the SCIEX 7500+ system, the most recent mass spectrometer within the SCIEX quantitative portfolio, constructing upon a legacy of dependable, delicate quantitation.
• The introduction of ZT Scan DIA, our subsequent era in data-independent acquisition (DIA), delivering the depth of protection attribute of DIA approaches however with the precision, sensitivity and selectivity of focused quantitative workflows.
• A collaboration between SCIEX and Mass Analytica on synthetic intelligence quantitation (AI quant) software program to course of knowledge and produce insights in a matter of moments.

The SCIEX 7500+ System. Picture Credit score: SCIEX

SCIEX launched the SCIEX 7500+ system while at ASMS. Are you able to clarify the important thing options of the brand new mass spectrometer system and the way it builds upon earlier fashions within the SCIEX quantitative portfolio?

Chris Lock: Via buyer collaborations, we all know that they want outcomes quicker whereas additionally guaranteeing higher system resilience, even with probably the most difficult pattern varieties like hashish, cosmetics, meals, or plasma. The SCIEX 7500+ system builds on the present robustness and reliability of the SCIEX 7500 system and has enhancements to extend uptime whereas sustaining sensitivity.

• Mass Guard expertise is a brand new proprietary expertise that features the power to actively filters out doubtlessly contaminating ions. It reduces the chance and frequency of instrument contamination, serving to to keep up the very best sensitivity for as much as 2X as lengthy in comparison with present SCIEX expertise, significantly when operating advanced matrices.
• DJet+ meeting is totally detachable, permitting front-end serviceability so clients can maximize the uptime of their programs.
• At 800 MRM per second, the SCIEX 7500+ system is the quickest SCIEX Triple Quad thus far. This will increase the scope for giant quantitation panels that want to include new compounds of curiosity, enhancing the general productiveness of the lab.
• Supported by new performance in SCIEX OS that permits customers to trace instrument efficiency and automate choice making, decreasing the potential for failed batches and repeat measurements.
• Compatibility with dry roughing pumps can cut back electrical energy consumption by 24% relative to oil-sealed pumps.”

Extracts from SCIEX Press Releases at ASMS 2024

With the power to course of 800 MRM per second, the SCIEX 7500+ system is the quickest Triple Quad from SCIEX. How does this velocity profit massive quantitation panels and lab productiveness?

Jose Castro-Perez: For pattern units which have numerous analytes being analyzed, a single LC/MS-MS pattern injection can be utilized as a substitute of a number of sub-sequent injections. This may even deal with velocity in methodology improvement for bigger panels.

SCIEX has additionally collaborated with Mass Analytica to current AI quantitation software program. Are you able to inform us extra in regards to the software program, its advantages, and the way it can course of knowledge from the SCIEX 7500+ system?

Jose Castro-Perez: As knowledge is generated at file speeds, the connective tissue stays how this knowledge might be processed for scientists to make real-time choices. The AI quantitative software program from this collaboration can produce insights shortly and enhance productiveness.

Amongst its many options is an AI-powered MRM transition prediction mannequin for triple quad programs such because the SCIEX 7500+ system. The predictor could be educated with consumer knowledge to enhance its accuracy. This characteristic saves time and sources by decreasing the need for compound infusions and situation optimizations.

The place can readers discover extra data?

1. www.sciex.com/7500plus
2. www.sciex.com/ztscandia
3. www.sciex.com/aiquantsoftware
4. https://www.sciex.com/merchandise/integrated-solutions/echo-ms-plus

In regards to the Interviewees:

Chris Lock, Vice President, World R&D, SCIEX.

As Vice President, World R&D, Chris is chargeable for software program and {hardware} Analysis and Growth for LCMS & CE at SCIEX.

Since becoming a member of SCIEX over 20 years in the past, Chris has held a number of technical and management roles with rising accountability. He has vital expertise working with product and market administration groups, and constructing sturdy cross-company relationships. Most just lately, he held the function of Vice President, LCMS R&D.

Previous to becoming a member of SCIEX, Chris labored as a Analysis Scientist on the Institute for Marine Biosciences, Nationwide Analysis Council Canada in Halifax. Chris holds a B.Sc. in Chemistry and a Ph.D. in Translational Power Spectrometry from the College of Wales, Swansea, UK.

Jose Castro-Perez, Vice President, Product Administration, SCIEX.

As Vice President, Product Administration, Jose is chargeable for the general possession of the worldwide SCIEX product portfolio for CE, LC/MS, software program ecosystems and equipment together with product line administration, expertise roadmap, new product improvement, and income/margin progress via worth creation and business help.

Jose has 25 years of expertise as a buyer in Pharma, CRO and the Biotech business. Along with this, he held a number of senior roles at Waters specializing in advertising and marketing and enterprise improvement for all services and products supplied.

Jose joined SCIEX in 2019 as a Senior Director in Correct Mass Product Administration overseeing the complete portfolio of Correct Mass merchandise. Throughout his tenure he was chargeable for the Correct Mass product line technique and the execution of that technique from ideation to end-of-life. Along with this, he additionally held a management function in Market Growth the place he was chargeable for creating the inbound and outbound advertising and marketing technique for the complete SCIEX product portfolio.

Jose holds a BSc in Chemistry from King’s School London, an MSc in Scientific Biochemistry and Molecular Biology from College of Surrey within the UK and a Ph.D. in Metabolomics from Leiden College within the Netherlands.