Scale Biosciences (ScaleBioTM), an innovator in accessible, versatile, and scalable single cell omics options, immediately introduced the supply of ScalePlex a complicated single cell multiplexing expertise designed to simplify large-scale single cell genomics research. With massively parallelized single cell barcoding and easy pattern multiplexing, ScalePlex allows final experimental flexibility from small to large-scale, multi-sample, multi-condition research whereas producing top quality information.
ScalePlex allows researchers to conduct experiments of any dimension and pattern quantity seamlessly, effectively, and cost-effectively. It does this by overcoming the restrictions of conventional lipid- or antibody-based single cell multiplexing applied sciences by using a novel modified oligo tag added throughout fixation. The easy workflow eliminates the necessity for particular person fixation and washing steps previous to pattern pooling in addition to eliminating upfront optimizations or titrations. By preserving treasured samples, ScalePlex is especially beneficial for researchers working with small organic tissue samples, comparable to these utilized in oncology and neuroscience experiments.
The scalability and effectivity of this expertise makes it potential to check a a lot bigger variety of samples and cells than is sensible with different applied sciences,” stated Alexander Bick, M.D., Ph.D., Assistant Professor of Medication at Vanderbilt College Medical Heart. “This new expertise is unlocking the chances of latest scientific frontiers by serving to researchers like me advance our understanding of the genetic foundation of illness.”
ScalePlex additionally helps large-scale CRISPR screening research together with high-throughput drug screening functions throughout many samples and circumstances at single cell decision. This technique leverages indexing to optimize present CRISPR screening approaches by deploying single cell genomics at scale.
The magic of our new ScalePlex answer is its simplicity. It provides researchers the final word flexibility to design experiments that don’t restrict scientific potential based mostly on outlined configurations. Our clients can count on this streamlined workflow to supply high-quality information whether or not they’re learning as few as 12 samples or greater than 300 circumstances,” stated Giovanna Prout, President and CEO of ScaleBio. “We have already acquired orders from main pharmaceutical and analysis clients on this environment friendly and uncomplicated method to multiplex samples. We consider this expertise will allow many extra researchers to undertake single cell omics throughout a variety of analysis disciplines.”
ScaleBio’s ScalePlex is out there for preorder and can start transport in July. For extra info, go to scale.bio/single-cell-rna-sequencing-kit/.
