Feb. 22, 2024 — Injectable weight reduction medication like Wegovy, Saxenda, and Zepbound have been getting all of the glory currently, however they’re not for everybody. In the event you’re trying to drop just a few kilos or forestall weight problems, analysis suggests there’s one other means. It may not produce outcomes as dramatic as common injections, however you may get all the things you want in a grocery retailer for a lot much less cash — and this strategy has the potential to enhance your well being in quite a few methods.
In idea, all it’s a must to do is increase your intestine microbiome.
“There are loads of various factors naturally in weight acquire and weight reduction, so the intestine microbiome is definitely not the one factor,” stated Chris Damman, MD, a gastroenterologist on the College of Washington. He research how meals and the microbiome have an effect on your well being. “With that caveat, it most likely is enjoying an necessary position.”
Trillions of Microbes
The concept that your intestine is dwelling to an unlimited vary of tiny organisms — microbes — has existed for greater than 100 years, however solely within the twenty first century have scientists had the flexibility to delve into specifics.
We now know you need a strong assortment of microbes in your intestine, particularly within the decrease intestine, your colon. They feast on fiber from the meals you eat and switch it into substances your physique wants. These substances ship alerts throughout your physique.
In the event you don’t have sufficient microbes or have too most of the incorrect varieties, it influences these alerts, which may result in well being issues. During the last 20 years, analysis has linked issues within the intestine microbiome to all kinds of situations, together with inflammatory bowel illness, autoimmune ailments like rheumatoid arthritis, metabolic ones like diabetes, and heart problems, bronchial asthma, and even autism.
Thanks to those efforts, we all know rather a lot concerning the interactions between your intestine and the remainder of your physique, however we don’t know precisely how many issues occur — whether or not some teeny critters inside your microbiome trigger the problems or vice versa.
“That is the issue with a lot of the microbiome stuff,” stated Elizabeth Hohmann, MD, a doctor investigator on the Massachusetts Normal Analysis Institute. “Olympic athletes have a greater intestine microbiome than most individuals. Properly, certain they do — as a result of they’re listening to their food plan, they’re getting sufficient relaxation. Correlation doesn’t causation make.”
The American Weight loss program Messes With Your Intestine
In the event you’re a typical American, you eat loads of ultra-processed meals — manufactured with a protracted elements listing that features components or preservatives. Based on one research, these meals make up 73% of our meals provide. That may have a critical impression on intestine well being.
“If you course of a meals and mill it, it turns a complete meals into tiny particles,” Damman stated. “That makes the meals extremely digestible. However if you happen to eat a stalk of broccoli, a considerable amount of that broccoli within the type of fiber and different issues will make its approach to your decrease intestine, the place it’s going to feed microbes.”
With closely processed meals, however, most of it will get digested earlier than it may well attain your decrease intestine, which leaves your microbes with out the power they should survive.
Rosa Krajmalnik-Brown, PhD, is director of the Biodesign Heart for Well being Via Microbiomes at Arizona State College. Her lab has executed analysis into how microbes use the undigested meals that reaches your intestine. She describes the issue with processed meals this manner:
“Take into consideration a Coke. If you drink it, all of the sugar goes to your bloodstream, and the microbes in your intestine don’t even know you’ve had it. As a substitute of ingesting a Coke, if you happen to eat an apple or one thing with fiber, some will go to you and a few to the microbes. You’re feeding them, giving them power.”
Weight and Your Intestine Microbiome
The hyperlink between intestine well being and physique weight has obtained loads of consideration. Analysis has proven, for instance, that folks with weight problems have much less variety of their intestine microbiome, and sure particular micro organism have been linked to weight problems. In animal research, transplanting intestine microbes from overweight mice to “germ-free” mice led these GF mice to acquire weight. This implies extra weight is, actually, brought on by sure microbes, however up to now there’s scant proof that the identical is true with people.
Krajmalnik-Brown’s group did an experiment through which they’d folks observe two completely different diets for 23 days every, with a break in between. Each offered comparable quantities of energy and macronutrients every day, however through completely different meals. The research’s typical Western menu featured processed meals — assume grape juice, sandwiches made with deli turkey and white bread, and spaghetti with jarred sauce and floor beef. The opposite menu, what researchers referred to as a “microbiome enhancer food plan,” included meals like entire fruit, veggie sandwiches on multigrain buns, and steak with a facet of entire wheat spaghetti.
Whereas the research wasn’t designed for weight reduction, an attention-grabbing factor occurred when researchers analyzed individuals’ bowel actions.
“We discovered that if you feed topics a food plan designed to offer extra power to the microbes and to not the [body], our topics misplaced a bit of weight,” Krajmalnik-Brown stated. “It seems like by feeding your microbes, it appears to make folks more healthy and doubtlessly even lose a bit of.”
One other doable mechanism entails the identical hormone that powers these injectable weight reduction medication. The decrease a part of your intestine makes hormones that inform your entire intestine to decelerate and in addition assist orchestrate metabolism and urge for food. Amongst them is GLP-1. The medication use an artificial model, semaglutide or tirzepatide, to set off the identical impact.
Based on Damman, you’ll be able to stimulate your intestine to make these useful hormones with the meals you eat — by giving your microbes the precise gasoline.
Eat to Feed Your Microbes
The meals you eat can have an effect on your intestine microbiome, and so your weight. However don’t go in search of that one good ingredient, specialists warn.
“Oftentimes we get this micro-focus, is that this a very good meals or a foul meals?” warned Katie Chapmon, a registered dietitian whose observe focuses on intestine well being. “You simply wish to be certain your microbiome is strong and wholesome, so it communicates that your physique is working, you’ve obtained it.”
As a substitute, attempt to give your physique extra of the varieties of meals analysis has proven can feed your microbiome, lots of that are plant-based. “These are the issues which can be largely taken out throughout processing,” Damman stated. He calls them the “4 Fs”:
- Fiber: If you eat fiber-rich meals like fruits, greens, entire grains, nuts, and beans, your physique can’t digest the fiber whereas it’s within the higher components of your GI tract. It passes by way of to your decrease intestine, the place wholesome micro organism ferment it. That produces short-chain fatty acids, which ship alerts all through your physique, together with ones associated to urge for food and feeling full.
- Phenols: Phenolic compounds are antioxidants that give plant-based meals their colour — if you speak about consuming the rainbow, you’re speaking about phenols. The microbes in your intestine feed on them, too. “My objective for a meal is 5 distinct colours on the plate,” Chapmon stated. “That rounds out the bases for the completely different polyphenols.”
- Fermented meals: You may get a special form of well being profit by consuming meals that’s already fermented — like sauerkraut, kimchi, kefir, yogurt, miso, tempeh, and kombucha. Fermentation could make the phenols in meals extra accessible to your physique. Plus, every mouthful introduces good micro organism into your physique, a few of which make it all the way down to your intestine. The micro organism which can be already there feed on these new strains, which helps to extend the range of your microbiome.
- Wholesome fat: Right here, it’s not a lot about feeding the great micro organism in your microbiome. Damman says that omega-3 fatty acids, present in fatty fish, canola oil, some nuts, and different meals, lower irritation within the lining of your intestine. Plus, wholesome fats sources like extra-virgin olive oil and avocados are stuffed with phenols.
Consuming for intestine well being isn’t a magic bullet by way of weight reduction. However the advantages of a wholesome intestine go far past shedding just a few kilos.
“I believe we have to try for well being, not weight reduction.” Krajmalnik-Brown stated. “Maintain your intestine wholesome and your microbes wholesome, and that ought to ultimately result in a wholesome weight. You’ll make your microbes blissful, and your microbes do rather a lot on your well being.”
